The Role Of Empiric Dilation In Patients With Dysphagia With Normal Endoscopy

Stopped early · Not applicable

Conditions studied: Dysphagia With Normal Endoscopy

In brief

The goal of our study is to determine if stretching the esophagus with a rubber dilator helps patients with swallowing difficulties who have a normal appearing esophagus on upper endoscopy. In order to do this we will perform a randomized controlled study, where patients will undergo esophageal dilation (stretching) with different diameter dilators. We will measure change in symptom severity between baseline (prior to dilation) and 1, 3, 6 and 12 months after the procedure

Key facts

Study ID

NCT01444066

Run by

Washington University School of Medicine

People needed

30

Starts

2011-09-01

Expected to finish

2013-10-24

Last updated by the study team

2020-06-18

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients age: > 18 years.
• Outpatients undergoing EGD for dysphagia.
• Ability to provide written informed consent.

You may not qualify if…

• Abnormal endoscopy (stricture, abnormal motility or mucosa observed)
• Oropharyngeal dysphagia suspected based on history and physical examination
• History of CVA or other neurologic disorder
• Known connective tissue disease (SLE, scleroderma, CREST, RA)
• Known histopathology based esophageal motor disorder, e.g. achalasia
• Prior thoracic or foregut surgery (excluding cholecystectomy)
• Prior thoracic radiation therapy
• Hiatus hernia >2 cm as judged during EGD

Where it is running

• Barnes Jewish Hospital — St Louis, Missouri, United States
• Washington University — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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