Developing Cognitive Training for Tourette Syndrome

Completed · Phase 1 · Has a placebo group

Conditions studied: Tourette Syndrome, Chronic Tic Disorders

In brief

Many researchers suspect that individuals with Tourette Syndrome (TS) may have a poor cognitive ability (i.e., response inhibition; RI) that is essential to inhibit inappropriate response such as vocal or motor tics. The investigators aim to test whether a well-established behavior therapy for TS can be improved by increasing the individual's RI capabilities. To this end, 20 children will be randomly assigned to behavior therapy with computer-based RI training or behavior therapy with placebo computer-based cognitive training. The investigators will test the hypothesis that computer-based RI training can be a useful addition to the well-established behavior therapy to enhance its therapeutic effect.

Key facts

Study ID: NCT01440023
Run by: University of Wisconsin, Milwaukee
People needed: 20
Starts: 2011-08-01
Expected to finish: 2014-12-01
Last updated by the study team: 2015-01-15

Who can join

Age: 9 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

age between 9 and 17
a diagnosis of TS or chronic tic disorder on the structured diagnostic interview
moderate to severe levels of tic symptoms (YGTSS total score > 13 for TS, or > 9 for CTD), and (d) IQ > 80.

You may not qualify if…

current substance abuse or dependence
current or past psychotic disorder, bipolar disorder, or schizophrenia
4 or more previous sessions of behavioral treatments for tic
significant suicidal ideation and/or attempts within the past 3 months
any recent (in the previous month) or planned change in medication for tic symptoms.

Where it is running

The Psychology Clinic, University of Wisconsin-Milwaukee — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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