Provitamin A Absorption and Conversion With Avocados
Completed · Not applicable
Conditions studied: Healthy
In brief
Vitamin A is necessary in the human diet. The form of vitamin A found in fruits and vegetables is not "active" and must be converted to the active form in the human body. However, information on the ability of humans to absorb and convert vitamin A to the active form is still lacking. In this study, the investigators will observe the absorption and conversion of vitamin A from orange tomato sauce and/or carrots after a meal with fat (from avocado fruit) and a meal without fat. The investigators will also test whether eating these foods might protect the blood against damage that could lead to heart disease.
Key facts
- Study ID
- NCT01432210
- Run by
- Ohio State University
- People needed
- 24
- Starts
- 2011-09-01
- Expected to finish
- 2012-03-01
- Last updated by the study team
- 2016-09-30
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Total cholesterol (140 to 200 mg/dL)
- BMI 17 to 30
- Age 18-70 years
You may not qualify if…
- Lactating, pregnant, or plan to be pregnant during study
- Tobacco use (cigarettes or chewing tobacco)
- Metabolic disease
- Malabsorption disorders
- History of cancer, esophageal, gastric, or intestinal ulcers
- History of liver or kidney insufficiency or failure
- Allergies to tomatoes or tomato products
- Allergies to carrots
- Allergies to avocados
- Obesity (BMI>30)
- Hypercholesterolemia (total cholesterol> 200mg/dL)
Where it is running
- The Ohio State University Clinical Research Center — Columbus, Ohio, United States
Full record on ClinicalTrials.gov
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