Measuring Adherence to Medication for Depression and Attention-deficit Hyperactivity Disorder

Completed

Conditions studied: Major Depressive Disorder, Attention-deficit Hyperactivity Disorder (ADHD)

In brief

Poor adherence is a common reason for treatment failure in many fields of medicine, and likely affects common psychiatric treatments as well. Members of the present study team have used Medication Event Monitoring System (MEMS®) caps effectively to objectively monitor adherence in skin disease, and have shown that they provide a much more accurate measure of adherence behavior than self-reports, pill counts, or serum drug concentrations. The present study will use MEMS® caps to measure adherence in 10 patients with depression and 10 patients with attention-deficit hyperactivity disorder (ADHD) from a student clinic population. The aims will be to show the usefulness of MEMS® caps in measuring adherence to psychiatric treatment, and gather data on typical adherence rates for depression and ADHD patients on typical treatment regimens. The data obtained will be used to inform future studies that use an intervention to improve adherence behavior and ultimately disease outcomes.

Key facts

Study ID

NCT01430767

Run by

Wake Forest University Health Sciences

People needed

33

Starts

2011-09-01

Expected to finish

2014-12-01

Last updated by the study team

2017-04-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any male or female, at least 18 years of age, using the Student Health Clinic, with a diagnosis of depression or ADHD.
• Written consent of participation must be given by the subject.

You may not qualify if…

• Subject is less than 18 years of age.
• Inability to complete all study-related visits.
• Introduction of any other prescription medication while participating in the study. (Patients who are on a stable dose of non-study-related prescription medications for at least 4 weeks prior to the study, and throughout the study period, are not excluded.)
• Female patients whose medications may be harmful during pregnancy must be on an acceptable form of birth control, otherwise they will not be eligible for participation.

Where it is running

• Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.