Matching Cognitive Remediation to Cognitive Deficits in Substance-Abusing Inmates
Completed · Not applicable
Conditions studied: Psychopathy, Personality Disorders
In brief
This is a 2 -year NIDA funded grant (Co-PIs: Joseph P. Newman, John Curtin, and Carl Lejuez) that examines whether recent progress in characterizing the cognitive deficits associated with psychopathic and externalizing offenders may be used to develop better therapeutic interventions to treat their substance abuse and other self-control problems. Inmates with externalizing or psychopathy will receive one of two computer-based interventions to remediate the core cognitive skills that have been linked to self-regulation deficits in the two groups. One intervention (ACC) targets the affective cognitive control deficits associated with externalizing offenders whereas the other intervention (ATC) targets the attention to context deficits associated with psychopathic offenders. The specific components of the project include: selection and randomization of inmates; pre- and post-treatment behavioral and brain-related (ERP and Startle) measures to evaluate the impact and specificity of the ACC and ATC treatments; and 6 sessions of behavioral (e.g. computerized) and verbal training in ACC or ATC.
Key facts
- Study ID
- NCT01428349
- Run by
- University of Wisconsin, Madison
- People needed
- 180
- Starts
- 2011-05-01
- Expected to finish
- 2013-05-01
- Last updated by the study team
- 2015-06-02
Who can join
Age: 18 and older, up to 45. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- Male,
- ages 18-45 years,
- elevated scores of psychopathy or externalizing measures
You may not qualify if…
- currently taking psychotropic medication,
- below a 4th grade reading level,
- history or current learning disability,
- history of head trauma with lasting effects,
- current diagnosis of PTSD,
- Bipolar, or
- psychosis
Where it is running
- Fox Lake Correctional Institution — Fox Lake, Wisconsin, United States
- Oshkosh Correctional Institution — Oshkosh, Wisconsin, United States
Full record on ClinicalTrials.gov
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