Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
Recruiting now
Conditions studied: Spontaneous Coronary Artery Dissection, SCAD
In brief
The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart. Some mutations may be inherited (passed on) from a parent without an apparent blood vessel problem while others may develop for the first time in the affected person.
Key facts
- Study ID
- NCT01427179
- Run by
- Mayo Clinic
- People needed
- 2000
- Starts
- 2011-05-01
- Expected to finish
- 2030-12-01
- Last updated by the study team
- 2026-04-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Men and women able to give informed consent and complete a 2 page questionnaire
- Diagnosis of one or more episodes of spontaneous coronary artery dissection (SCAD)
- Biological parent of individual with SCAD
- Relative with fibromuscular dysplasia, arterial aneurysm, or arterial dissection
You may not qualify if…
- Lack of confirmation of SCAD diagnosis
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States (enrolling)
Full record on ClinicalTrials.gov
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