Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis

Completed · Not applicable · Has a placebo group

Conditions studied: Rheumatoid Arthritis, Vitamin D Deficiency

In brief

The purpose of this study is to investigate the effect of vitamin D repletion on disease activity and disability in patients with rheumatoid arthritis. The investigators hypothesize that rheumatoid arthritis (RA) patients with vitamin D deficiency have greater disease activity and disability, compared to RA patients with normal vitamin D levels. The investigators also hypothesize that vitamin D treatment in these deficient patients will result in a decrease in RA disease activity and disability.

Key facts

Study ID

NCT01426347

Run by

Johns Hopkins University

People needed

139

Starts

2009-01-01

Expected to finish

2012-01-01

Last updated by the study team

2017-03-20

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Rheumatoid Arthritis diagnosed according to American College of Rheumatology (ACR) criteria
• ages 18-75 years

You may not qualify if…

• Diagnosis of any other autoimmune disease:
• such as Lupus, Scleroderma, Myositis, Sjogren's Syndrome, Vasculitis'
• Having any of the following conditions with in the last 6 months Hypercalcemia, Hyperparathyroidism, Active tuberculosis (TB), Lymphoma or any other type of cancer, Sarcoidosis, Seizure, Stroke
• Severe heart problems
• Kidney failure requiring dialysis treatment
• Liver failure or cirrhosis of the liver
• Poorly controlled hypertension
• current uncontrolled Depression, Bipolar Disorder, or other Psychiatric illness
• Pregnancy

Where it is running

• Johns Hopkins University — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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