Evaluation of a Cognitive Adaptive E-treatment in Schizophrenia-diagnosed Adults
Completed · Phase 2
Conditions studied: Schizophrenia
In brief
This study is a multi-site, double-blind, randomized, controlled clinical trial to assess the safety and effectiveness of plasticity-based, adaptive, computerized-based cognitive remediation treatment versus a computer-based control. The investigators proposed that a computerized cognitive remediation program based upon the principles of brain plasticity may improve information processing and thus drive clinically significant improvements in cognitive and functional performance in individuals with schizophrenia.
Key facts
- Study ID
- NCT01422902
- Run by
- Posit Science Corporation
- People needed
- 150
- Starts
- 2012-04-01
- Expected to finish
- 2015-06-01
- Last updated by the study team
- 2016-02-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years of older with confirmed diagnosis of Schizophrenia
- Adequate decisional and reading capacity
- Clinical stable
- Moderate or less severity on Positive and Negative Symptoms Scale
- English speaker
- Capable of completing clinical and cognitive assessment battery
- Lack of visual, auditory or motor capacity to participate in the study
- Minimal level of extrapyramidal symptoms
- Minimal level of depressive symptoms
You may not qualify if…
- Failure to meet suicidality rating criteria
- Prescribed greater than 2 anti-psychotics
- Significant alcohol and illicit drug use
- History of mental retardation or pervasive developmental disorder or other neurological disorder
- Prior specified computer-based cognitive remediation training
- Participation in a concurrent study that could affect the outcome of this one
Where it is running
- Palo Alto Veteran's Affairs Medical Center — Palo Alto, California, United States
- Posit Science Corporation — San Francisco, California, United States
Full record on ClinicalTrials.gov
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