Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular Disease

Completed

Conditions studied: Exercise Tolerance, Dyspnea, Heart Failure, Pulmonary Hypertension

In brief

Heart Failure with Preserved Ejection Fraction (HFpEF) and Pulmonary Hypertension (PH) can be diagnosed noninvasively by Exercise Echocardiography (ExE) and Cardiopulmonary Exercise Testing (CPX) as compared with gold standard invasive hemodynamic assessment.

Key facts

Study ID

NCT01418248

Run by

Mayo Clinic

People needed

108

Starts

2011-08-01

Expected to finish

2013-08-01

Last updated by the study team

2014-01-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• exertional intolerance/dyspnea of unknown etiology
• referral to cardiac catheterization laboratory
• undergoing invasive hemodynamic evaluation for clinical purposes

You may not qualify if…

• hypertrophic cardiomyopathy
• constrictive pericarditis
• infiltrative myopathy (e.g. amyloid)
• congenital heart disease
• resting LVEF <50%
• > moderate mitral annular calcification
• moderate or greater left-sided valvular stenosis or regurgitation
• prior valve surgery
• basal septal wall motion abnormalities
• >70% epicardial coronary artery stenosis
• right ventricular infarction
• pregnancy

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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