Effects of Breast Feeding on Post-Cesarean and Post-Vaginal Delivery Pain
Completed
Conditions studied: Pain
In brief
Oxytocin is a hormone that is released in response to distension of the cervix and uterus during labor, and after breast feeding as a result of nipple stimulation. In addition to oxytocin facilitating birth and breastfeeding, oxytocin has a number of effects on maternal behavior including bonding, social recognition, anxiolysis, sexual arousal. The role of oxytocin in pain modulation has recently been highlighted. Intranasal or intrathecal (spinal) administration has been found to impact pain modulation. The administration of intravenous oxytocin has not provided effective analgesia because oxytocin is unable to pass to your brain. The role of breastfeeding on analgesia is poorly investigated, which is why we are carrying out this study.
Key facts
- Study ID
- NCT01417260
- Run by
- Stanford University
- People needed
- 130
- Starts
- 2011-08-01
- Expected to finish
- 2014-12-01
- Last updated by the study team
- 2015-04-14
Who can join
Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 - 40 yrs
- ASA 1 or 2
- Singleton gestation
- Greater or equal to 37 weeks gestation
- Vaginal delivery
- Scheduled cesarean delivery with a Pfannenstiel incision
You may not qualify if…
- Chronic pain
- Patients prescribed regular analgesia medication ante-natally
- Substance abuse
- Classical cesarean incision
- Emergency cesarean delivery
- Patients not planning to breastfeed
- Psychiatric or cognitive disorder, including anxiety or depression
- Physicians, labor and delivery nurses, midwives
Where it is running
- Stanford University School of Medicine — Stanford, California, United States
Full record on ClinicalTrials.gov
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