Efficacy of Olibra: A 12 Week Controlled Trial
Completed · Phase 1/Phase 2 · Has a placebo group
Conditions studied: Overweight, Obesity
In brief
Today's obesogenic environment, favors behavioral choices that lead to an excess of energy intake over expenditure, and consequently weight gain. Intervention strategies that harness the body's own appetite and satiety regulating signals could provide an effective means of countering excessive energy intake. The purpose of this study was to investigate whether a vegetable oil emulsion (Olibra) would result in weight loss that was associated with a reduction in food intake.
Key facts
- Study ID
- NCT01416051
- Run by
- Pennington Biomedical Research Center
- People needed
- 82
- Starts
- 2005-01-01
- Expected to finish
- 2006-11-01
- Last updated by the study team
- 2015-12-18
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy subjects of both sexes 18 - 60 years of age
- body mass index (BMI) between 25 and 40 kg/m2, inclusive
You may not qualify if…
- (1) participation in another clinical trial or receipt of an investigational product 30 days prior to enrollment
- (2) a dietary restraint score of > 13
- (3) weight loss of 4.5 kg or more in the preceding three months
- (4) use of tobacco products, nicotine gum or nicotine patch
- (5) a medical condition or taking regular medication except oral contraceptives and hormone replacement therapy
- (6) use of a nutritional product or dietary supplement or program which might interfere with the conduct of the study or place the subject at risk
- (7) history of alcohol or other drug abuse in the preceding one year
- (8) pregnancy, lactation, post-partum less than six months, planning a pregnancy during the study or not using an acceptable method of contraception
- (9) fasting blood sugar ≥ 126 mg/dl
- (10) known allergy or sensitivity to any ingredient in the supplement
- (11) clinically significant deviations in normal laboratory values
- (12) irregular meal-times, and
- (13) unwilling to eat yogurt at test meals.
Where it is running
- Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States
Full record on ClinicalTrials.gov
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