Alprazolam and Eating Behavior in Anorexia Nervosa

Completed

Conditions studied: Anorexia Nervosa

In brief

This study examines the role of anxiety in food intake among patients with AN by measuring caloric intake in a standardized, laboratory meal with alprazolam versus a placebo. Patients will participate in two test meal sessions, one after receiving alprazolam and one after receiving a placebo. Patients will be administered psychological measures of anxiety, mood, and eating behavior. Primary outcomes include caloric intake in a laboratory test meal and pre-meal anxiety levels.

Key facts

Study ID

NCT01411813

Run by

New York State Psychiatric Institute

People needed

19

Starts

2010-11-01

Expected to finish

2011-10-01

Last updated by the study team

2012-11-02

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• DSM-IV-TR™ diagnosis of anorexia nervosa (restricting or binge-purge subtype), with or without amenorrhea at the time of inpatient admission.
• Older than 18
• No acute medical condition
• Participation in inpatient treatment
• Subjects must have signed informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study.

You may not qualify if…

• Psychotic or bipolar I disorder
• Substance abuse or dependence in the last 6 months
• Current Axis I disorder requiring psychotropic medication (subjects taking a stable dose of psychiatric medications will be allowed.)
• Active suicidal intent.

Where it is running

• New York State Psychiatric Institute — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.