Occult Paroxysmal Atrial Fibrillation in Patients With Non-cardioembolic Ischemic Stroke of Determined Mechanism
Completed
Conditions studied: Atrial Fibrillation, Stroke
In brief
The aim of this study is to determine the yield of 3 weeks outpatient mobile cardiac monitoring for detection of atrial fibrillation in patients with history of stroke of known cause.
Key facts
- Study ID
- NCT01410396
- Run by
- Northwestern University
- People needed
- 49
- Starts
- 2010-04-01
- Expected to finish
- 2013-05-01
- Last updated by the study team
- 2013-08-15
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age > 50
- Ischemic stroke, or transient ischemic attack with documented acute brain infarction, within prior 6 months.
- Patient does not merit indefinite oral anticoagulation. (Patients requiring temporary OAC for purposes other than recurrent stroke prevention, such as treatment of a deep venous thrombosis, are eligible for enrollment if the long-term secondary stroke preventive strategy is anti-platelet therapy and not OAC).
- Stroke mechanism is determined to be lacunar stroke, large vessel intracranial atherosclerosis, large vessel extracranial atherosclerosis, or a combination thereof.
- Patient has been evaluated with at least a 12 lead EKG and at least one day of in-patient or out-patient cardiac telemetry, with no detection of AF or atrial flutter.
- Detection of AF or atrial flutter would change secondary prevention antithrombotic strategy (eg to indefinite OAC).
- Patient receives and successfully activates LifeStar ACT device.
- Patient or legally authorized representative signs informed consent.
You may not qualify if…
- Known history of AF or atrial flutter.
- Patient has defibrillator or pacemaker capable of detecting AF.
- Patient has indication for indefinite OAC.
- Patient has indefinite contra-indication to OAC. (Patients with temporary ineligibility for OAC, for example due to the need for invasive medical procedures or large acute brain infarction, are eligible for enrollment).
- Stroke due to known cause not listed in inclusion criterion 4.
- Cardioembolic stroke.
- Inability to comply with LifeStar ACT monitoring regimen.
Where it is running
- Northwestern University — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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