High-Resolution Diffusion Tensor Imaging (DTI) of the Cervical Spinal Cord in the Setting of Spinal Cord Injury (SCI)
Completed
Conditions studied: Spinal Cord Injury, Cervical Spondylosis With Myelopathy, Degenerative Disorder
In brief
The investigators propose a prospective study, designed to analyze the efficacy of High-Resolution Diffusion Tensor Imaging for accurately sensing white matter tracts in subjects with spinal cord injury. Study subjects will not be randomized, as treatment will follow the doctor's "standard of care." Patients will be selected and offered enrollment based upon the clinical diagnosis of spinal cord injury, either due to degenerative disease or trauma. Enrollment will be based on the chronology of patient presentation.
Key facts
- Study ID
- NCT01407705
- Run by
- University of Utah
- People needed
- 31
- Starts
- 2007-05-01
- Expected to finish
- 2014-05-01
- Last updated by the study team
- 2014-05-21
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- For inclusion to the Cervical Spinal Cord (CSM)
- Clinical and Radiographic evidence of cervical spondylotic myelopathy
- 18 to 80 years of age
- Safe and stable clinical scenario to undergo imaging
- Awake, alert patient able to cooperate with physical examination
- Give written informed consent prior to any testing under this protocol
- For inclusion to the Control Group, subject must have:
- No diagnosis of cervical degenerative or traumatic disease
- 30 to 80 years of age
- Ability of volunteers to tolerate 1 hr examination
- For inclusion to the Degenerative Disease Group, subject must:
- Have signs or symptoms consistent with spinal cord injury.
- Be diagnosed with cervical spondylosis (degenerative disease).
- For inclusion to the Traumatic Group, subject must have:
- A spinal cord injury associated with a traumatic event.
You may not qualify if…
- For exclusion to the Cervical Spinal Cord (CSM):
- Unsafe or unstable clinical scenario
- Prior cervical spine surgery
- History of neurological disease (stroke, multiple sclerosis, peripheral neuropathy, or other neurodegenerative conditions)
- Inability to comply with physical examination
- Contraindications to MRI imaging (metal debris, cardiac pacemaker, etc..)
- Pregnant women
- For exclusion to the other groups:
- Inability to comply with physical examination
- Contraindications to MRI imaging (metal debris, cardiac pacemaker, etc..)
- Pregnant women
Where it is running
- University of Utah Orthopedics — Salt Lake City, Utah, United States
Full record on ClinicalTrials.gov
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