Droperidol Versus Metoclopramide + Diphenhydramine for the Treatment of Primary Headaches
Stopped early · Not applicable
Conditions studied: Primary Headaches (Includes Migraines, Tension, Cluster Headaches)
In brief
The purpose of this study is to determine if droperidol is equally as effective as metoclopramide for treatment of primary headaches in the Emergency Department.
Key facts
- Study ID
- NCT01406860
- Run by
- University of Iowa
- People needed
- 19
- Starts
- 2011-07-01
- Expected to finish
- 2012-07-01
- Last updated by the study team
- 2017-12-05
Who can join
Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 18 years old to 65 years old, diagnosis of primary headache
You may not qualify if…
- Allergy to study medications, pregnant, breast-feeding, prisoners, non-english speaking, not eligible to receive droperidol based on ED protocol (see below), patients in whom head trauma, infection, vascular disorders, and disorders of facial or cranial structures are suspected
- ED Droperidol Protocol
- Droperidol must NOT be used in patients with any of the following:
- Known or suspected QT prolongation, including congenital long QT syndrome
- Cardiac Disease [cardiomyopathy, congestive heart failure, hypertension, ischemic heart disease, myocardial infarction, bradycardia (< 50 bpm)]
- History of the following:
- Renal failure
- Cerebrovascular disease
- Diabetes or hypoglycemia
- Alcoholism/alcohol abuse
- Pituitary insufficiency
- Hypothyroidism
- Hypothermia
- Anorexia
- Advanced age (>65 yrs)
- Use of the following medications: digoxin, benzodiazepine, diuretics, IV opiates, or other medications known to prolong the QTc interval.
Where it is running
- University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
Full record on ClinicalTrials.gov
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