Investigating Motor Cortex Processing for Pain Modulation

Stopped early · Phase 1 · Has a placebo group

Conditions studied: Motor Activity

In brief

The purpose of this study is to investigate the effects of different types of interventions (motor learning, somatosensory learning, observation task, mental imagery and tDCS) on the perception of pain and motor cortex excitability in healthy male subjects. This is an exploratory study of healthy subjects only.

Key facts

Study ID

NCT01404039

Run by

Spaulding Rehabilitation Hospital

People needed

115

Starts

2010-09-01

Expected to finish

2014-04-01

Last updated by the study team

2020-04-24

Who can join

Age: 18 and older, up to 64. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Provide informed consent to participate in the study
• 18 to 64 years old
• No presence of rheumatologic disease as self reported
• No clinically significant or unstable medical or psychiatric disorder as self reported
• No history of alcohol or substance abuse within the last 6 months as self reported
• No neuropsychiatric co-morbidity as self reported
• No Contraindications to single pulse TMS (TMS will be used to measure cortical excitability)
• history of seizures
• unexplained loss of consciousness
• metal in the head
• frequent or severe headaches or neck pain
• implanted brain medical devices
• No Contraindications to tDCS
• metal in the head
• implanted brain medical devices

Where it is running

• Spaulding Rehabilitation Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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