Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics

Completed · Not applicable

Conditions studied: Methemoglobinemia

In brief

To establish and compare maximum methemoglobin blood levels and times to maximum methemoglobin blood levels following the administration of the injectable local anesthetics prilocaine and lidocaine when used for dental treatment in pediatric patients under general anesthesia. Patients will be randomized into three equal study groups. Two of the study groups will receive local anesthetic and the third group will not. Methemoglobin blood levels will be non-invasively monitored and recorded throughout dental treatment for all groups using a Masimo Radical-7 Pulse Co-Oximeter device.

Key facts

Study ID

NCT01402869

Run by

Loma Linda University

People needed

91

Starts

2011-08-01

Expected to finish

2012-07-01

Last updated by the study team

2014-04-25

Who can join

Age: 3 and older, up to 5. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patient scheduled to undergo comprehensive dental treatment under general anesthesia at the Koppel Special Care Dentistry Center at Loma Linda University School of Dentistry
• ASA I or II health status
• Age greater than 3 years but less than 6 years
• Weigh between 10kg and 25kg

You may not qualify if…

• Patient not requiring restorative dental treatment
• Have a BMI less than the 5th percentile or greater than the 95th percentile for their age and gender

Where it is running

• Loma Linda University School of Dentistry Koppel Special Care Dentistry Center — Loma Linda, California, United States

Full record on ClinicalTrials.gov

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