Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol

Completed · Phase 4

Conditions studied: Complication of Injection, Pain

In brief

The purpose of this study is to compare the incidence and intensity of possible pain on injection as well as patient satisfaction caused by propofol (a lipid based medication); Lusedra (a water based medication); and the drug combination of propofol with lidocaine (a local anesthetic commonly used with propofol injection).

Key facts

Study ID

NCT01401049

Run by

NYU Langone Health

People needed

116

Starts

2010-08-01

Expected to finish

2013-01-01

Last updated by the study team

2017-12-29

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• American Society of Anesthesiologists (ASA) I, II or III.
• Age 18 - 65.
• Both male and female.
• No significant laboratory abnormalities.

You may not qualify if…

• Chronic pain patients or patients receiving benzodiazepines or opioids / other analgesics for control of acute pain will be excluded.
• Patients with known allergies to any of the study drugs, or to soybean oil or egg lecithin are excluded.
• Women with a positive pregnancy test reported from pre-surgical testing or their physician's office or who are breast feeding at the time of surgery.
• No emergency patients will be recruited for this study.

Where it is running

• NYU Langone Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

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