A f-MRI Study Of Affective Changes Associated With Four Weeks Consumption Of A Fermented Dairy Product In Healthy Women

Completed · Not applicable

Conditions studied: Healthy Adult Women

In brief

The purpose of this study is to evaluate the effect of a commercially available fermented dairy product containing probiotics (4 weeks, twice a day) on the brain activity within specific neural circuits regulating the subjective experience of emotional valence and digestive well-being.

Key facts

Study ID: NCT01398163
Run by: Danone Global Research & Innovation Center
People needed: 51
Starts: 2009-04-01
Expected to finish: 2010-12-01
Last updated by the study team: 2016-11-25

Who can join

Age: 18 and older, up to 60. Sex: female. Healthy volunteers: accepted.

You may qualify if…

Healthy women, right-handed, aged from 18 to 60 years
Subject of normal body weight or with overweight i.e. not obese (body mass index between 18 and 30 kg/m2).
For fertile women, complying with one of the other medically approved methods of contraception

You may not qualify if…

Subject with any current psychiatric or eating or suicidal attempt disorder, or history of such disorder.
Subject with any history of chronic GI disorder or disease.
Subject with any significant active or prior metabolic disorder or disease.
Subject with any use of probiotic supplements or antibiotics in the previous month.
Subject with current use of any medications with potential central nervous system effects (antidepressants, anxiolytics, opiate pain medications...).
Subject with allergy or hypersensitivity to milk proteins or lactose intolerance or immunodeficiency
Subjects with claustrophobia or other condition (such as metallic implants) that would preclude MRI scanning

Where it is running

UCLA - University — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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