Histologic Evaluation of Healing Following Tooth Extraction With Ridge Preservation Using NuOss XC and NuOss Particulate

Completed

Conditions studied: Oral Ridge Preservation

In brief

This study histologically evaluates sites grafted with NuOss XC using ridge preservation techniques prior to placement of dental implants. Sites grafted with NuOss XC (bovine bone mineral with self-expanding collagen) will be compared to sites grafted with NuOss particulate (bovine bone mineral).

Key facts

Study ID

NCT01391767

Run by

University of Oklahoma

People needed

22

Starts

2011-07-01

Expected to finish

2013-05-01

Last updated by the study team

2013-07-08

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• may be either male or female
• must be between 18 and 64 years old
• must be of sufficiently good health to undergo routine dental treatment, including the surgical procedures associated with tooth extraction and placement of NuOss XC or NuOss particulate
• must agree to remain in study for 6 months after ridge preservation (grafting)
• must be able to physically, emotionally, and financially undergo the surgical and restorative (implant replacement) procedures planned.
• must not have medical conditions that preclude the removal of indicated teeth and placement of NuOss XC or NuOss particulate
• must have at least one single-rooted tooth to be extracted
• must consent to tooth extractions, socket augmentation and implant placement
• Patients with or without dental insurance

You may not qualify if…

• have any requirements for antibiotic premedication for heart murmurs, artificial joints, or any other condition
• have a history of significant heart, stomach, liver, kidney, blood, immune system or other organ impairment or systemic disease that would prevent their undergoing the proposed treatment
• smoke ≥ 10 cigarettes per day or use other tobacco products
• have a religious or philosophical aversion to having processed bovine bone or collagen used in their mouth
• have taken any investigational drugs anytime in the previous month
• have dental conditions likely to require treatment, necessitating exit from the study such as deep caries, abscesses, or moderate-severe periodontal disease(s).
• have sockets that do not have four bony walls intact.
• cannot comply with treatment and follow-up visits for 6 months
• have had significant radiation exposure (occupational, therapeutic, diagnostic).

Where it is running

• University of Oklahoma College of Dentistry — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

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