DIBH Proton Planning
Completed
Conditions studied: Lung Cancer, Breast Cancer, Gastrointestinal, Lymphomatous Malignancies
In brief
The overall objective is to estimate the actual or potential benefit of deep inspiration breath holding (DIBH) treatment in the context of proton radiotherapy as compared to 3 dimensional conformal radiation therapy (3DCRT) and intensity-modulated x-ray therapy (IMXT), as it relates to variability in tumor localization, treatment margins, target volume definition, doses to organs at risk and variations with treatment planning.
Key facts
- Study ID
- NCT01386697
- Run by
- Abramson Cancer Center at Penn Medicine
- People needed
- 40
- Starts
- 2010-11-01
- Expected to finish
- 2013-06-01
- Last updated by the study team
- 2020-03-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 and older
- Biopsy-proven malignancy
- The diagnosis of hepatocellular carcinoma may be made on a clinical basis without the need for a biopsy if the following criteria are met: a) Documentation of hepatitis B or C infection b)Liver mass with characteristic imaging (CT or MRI) features of hepatocellular carcinoma c) Alpha-feta protein (AFP) level greater than 20 ng/mL 3. Planned curative external beam RT as part of the patients treatment for the cancer diagnosis.
- Subject must be cable of giving informed consent for standard external beam radiation therapy as well as for the study.
- Subjects must be able to tolerate the deep inspiration breath hold (DIBH) training and procedures.
You may not qualify if…
- Subjects unsuitable for or unable to undergo definitive external beam, radiation therapy for their diagnosis of cancer
- Subjects undergoing radiation with palliative (i.e., non-curative) intent.
- Subjects unwilling to undergo simulation with the SpiroDynrX (SDX) system.
- Subjects unable to hold their breath for a minimum of 10 seconds.
Where it is running
- Abramson Cancer Center of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.