Exercise in Treatment Resistant Depression (TRD): A Feasibility Study
Completed · Not applicable
Conditions studied: Treatment Resistant Depression
In brief
The objective of this study is to determine the effects of adjunct exercise in treatment resistant depression. The central hypothesis for the research is that adjunct exercise with usual care in Treatment Resistant Depression (TRD) will have significant effects in improving the psychiatric symptoms in comparison to usual care alone.
Key facts
- Study ID
- NCT01383811
- Run by
- Milton S. Hershey Medical Center
- People needed
- 21
- Starts
- 2011-06-01
- Expected to finish
- 2013-06-01
- Last updated by the study team
- 2014-03-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Being sedentary (exercising less than 3 times/week for > 20 minutes at moderate/vigorous intensity for each bout)
- Ability to come for supervised exercises up to 5 days/week.
- On stable doses of medication or psychotherapy (within last 1 month) for underlying depression and willingness to continue on stable dose or therapy schedule during active phase of study participation, with the exception of during acute exacerbation of symptoms of psychiatric illness.
- Being able to read, understand, and provide written informed consent.
You may not qualify if…
- DSM-IV TR Axis I diagnosis of bipolar disorder, schizophrenia or schizophrenia spectrum disorder, or substance or alcohol abuse/dependence disorder (except nicotine dependence) in the past 12 months. Patients with current primary anxiety disorder will also be excluded.
- Behavioral or personality disturbances, which may significantly interfere with study participation.
- Evidence of acute suicidal risk.
- Medical contraindication for physical exercise (significant orthopedic or cardiopulmonary disorder) that would prevent regular aerobic exercise. The American College of Sports Medicine criteria for risk stratification will be used and where indicated medical clearance for exercise will be obtained through the subject's primary care physician.
- Pregnancy.
Where it is running
- Penn State Hershey Medical Center — Hershey, Pennsylvania, United States
Full record on ClinicalTrials.gov
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