Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Inflammatory Response

In brief

The administration of anti-inflammatory drugs such as ibuprofen before and after surgery has not been studied extensively. Subjects are being asked to participate in this study because they are scheduled for surgery and because the investigators want to study ways to improve recovery from surgery. Ibuprofen will be given several times before and after surgery. The investigators will ask questions to determine recovery and the investigators will draw blood to determine inflammatory response.

Key facts

Study ID: NCT01377441
Run by: NYU Langone Health
People needed: 6
Starts: 2011-09-01
Expected to finish: 2013-05-01
Last updated by the study team: 2017-12-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Adults, 18 and over, who will undergo surgery lasting longer than one hour with general anesthesia
Subject is non-lactating and is either:
Not of childbearing potential
Of childbearing potential but is not pregnant at time of baseline as determined by pre-surgical pregnancy testing.
Subject is ASA physical status 1, 2, or 3

You may not qualify if…

Cognitively impaired (by history)
Subject requires chronic antipsychotic history
Subject is anticipated to require an additional surgery within 90 days after the intended surgery
Chronic use of steroids or opioids
Subject has received treatment with COX inhibitors within 3 days of study entry
Subject for whom opiates, benzodiazepines, and COX inhibitors are contraindicated

Where it is running

NY Methodist Hospital — Brooklyn, New York, United States
NYU Langone Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.