Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Stroke, Problem of Aging

In brief

The purpose of this study is to find out if quercetin can increase blood levels of hypoxia-inducible transcription factor 1 (HIF-1 protein) and to see if there is a corresponding increase in blood flow to the brain.

Key facts

Study ID

NCT01376011

Run by

Brigham and Women's Hospital

People needed

106

Starts

2009-06-01

Expected to finish

2014-12-01

Last updated by the study team

2015-01-28

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy volunteers between the ages of 18-75 years old

You may not qualify if…

• subjects taking vasoactive medications
• hypertension or vascular disease
• asthma
• smokers
• pregnant women
• cancer
• diabetes mellitus
• history of seizures
• history of stroke or head trauma
• subjects taking digoxin, cyclosporine,felodipine, estradiol, or quinolone antibiotics
• poor transcranial Doppler insonation windows

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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