Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma

Completed

Conditions studied: Localized Osteosarcoma, Metastatic Osteosarcoma, Osteoblastic Osteosarcoma, Recurrent Osteosarcoma

In brief

This research study is studying biomarkers in predicting response to chemotherapy in samples from young patients with osteosarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

Key facts

Study ID

NCT01374672

Run by

Children's Oncology Group

People needed

20

Starts

2011-07-01

Expected to finish

2011-09-01

Last updated by the study team

2015-05-12

Who can join

Age: 10 and older, up to 20. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with high-grade osteoblastic osteosarcoma
• Biopsy samples from patients who had good or poor response to neoadjuvant chemotherapy available
• All specimens should be from post-menarchal females or age-matched males with appendicular tumors
• Patients' clinical data including chemotherapy received, event-free survival, and overall survival available
• See Disease Characteristics

Where it is running

• Children's Oncology Group — Monrovia, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.