Trial of Collaborative Depression Care Management for HIV Patients
Completed · Not applicable
Conditions studied: Depression, HIV
In brief
This project will integrate a depression treatment and brief medication adherence counseling intervention into clinical care at three HIV clinics and will use a randomized controlled trial to assess whether, relative to usual care, the intervention leads to improved HIV medication adherence. The depression treatment intervention uses a model known as Measurement-Based Care which equips Depression Care Managers with systematic measurement tools, a decision algorithm, and psychiatric backup and trains them to provide decision support to HIV clinicians to implement, monitor, and adjust antidepressant therapy.
Key facts
- Study ID
- NCT01372605
- Run by
- Duke University
- People needed
- 304
- Starts
- 2010-04-01
- Expected to finish
- 2014-06-01
- Last updated by the study team
- 2016-11-29
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18-65
- HIV-positive
- Patient Health Questionnaire-9 (PHQ-9) total score >= 10
- Confirmed current major depressive episode
- English-speaking
You may not qualify if…
- History of bipolar disorder
- History of psychotic disorder
- Failure of adequate trials of two different antidepressants at effective doses in the current depressive episode
- Current substance dependence requiring inpatient hospitalization
- Not mentally competent
- Acute suicidality or other psychiatric presentation requiring immediate hospitalization
Where it is running
- University of Alabama at Birmingham 1917 Clinic — Birmingham, Alabama, United States
- University of North Carolina Hospitals Infectious Diseases Clinic — Chapel Hill, North Carolina, United States
- Duke University Clinic 2J — Durham, North Carolina, United States
- Northern Outreach Clinic — Henderson, North Carolina, United States
Full record on ClinicalTrials.gov
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