Glycemic Effects of Honey

Completed · Not applicable

Conditions studied: Pre-diabetes

In brief

Honey has been used as a sweetener for centuries. Recent data indicate that honey consumption may have beneficial effects upon glucose intolerance, a health issue currently affecting 57 million Americans of every age and ethnicity. In order to evaluate the glycemic effect of honey, the investigators will carry out a human trial assessing biomarkers of blood glucose responses, insulin sensitivity, oxidative stress, and inflammatory markers. Our primary objective is to determine the glycemic effects of honey in comparison to sucrose and high fructose corn syrup (HFCS). The investigators hypothesize that honey will promote improved glucose tolerance and insulin sensitivity compared to both sucrose and high fructose corn syrup in normal glycemic and glucose intolerant adults.

Key facts

Study ID

NCT01371266

Run by

USDA Grand Forks Human Nutrition Research Center

People needed

55

Starts

2011-06-01

Expected to finish

2015-08-01

Last updated by the study team

2018-08-03

Who can join

Age: 20 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men and women between 20-80 years of age.
• Normal Glucose Tolerance
• Fasting glucose between ≤105 mg/dl
• Normal body weight or overweight (BMI 18-29.9)
• Impaired Glucose Tolerance
• Fasting glucose between 106-125 mg/dl
• Overweight or obese (BMI 25 - 39.9)
• Willingness to comply with the demands of the experimental protocol
• Sedentary Lifestyle

You may not qualify if…

• Known uncontrolled disease process
• Diabetes mellitus
• Use of medications that affect glucose metabolism
• History of an eating disorder
• Pregnancy or breast feeding
• Inability to give consent
• Unwillingness or inability to consume the supplemental sugars

Where it is running

• Grand Forks Human Nutrition Research Center — Grand Forks, North Dakota, United States

Full record on ClinicalTrials.gov

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