The NICHD Fetal Growth Study: Twin Gestations

Completed

Conditions studied: Fetal Growth Restriction, Growth Discordancy

In brief

Normal growth and development of twins are important for the long-term health of the children. The purpose of this study was to empirically define the trajectory of fetal growth in dichorionic twins using longitudinal two-dimensional ultrasonography and to compare the fetal growth trajectories for dichorionic twins with those based on a growth standard developed by our group for singletons. This knowledge may lead to interventions that could minimize or prevent pregnancy and newborn health problems in the future.

Key facts

Study ID

NCT01369940

Run by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

People needed

171

Starts

2011-05-29

Expected to finish

2014-09-30

Last updated by the study team

2017-09-05

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Twin, viable pregnancy
• 8+0 13+6 weeks of gestation
• Maternal age 18 - 45 years
• Spontaneous pregnancy or pregnancy from ovulation induction or in-vitro fertilization with known date of transfer
• Pregnancy from egg donor or embryo donor (record if anonymous or known source)
• LMP-date and crown-rump length measurement match within certain number of days according to a standard scheme (for larger twin)
• Expect to deliver at one of the participating hospitals

You may not qualify if…

• Fetal reduction (medically induced only)
• Congenital anomalies (structural or chromosomal)
• Either twin with an increased nuchal translucency (>99th percentile for crown-rump length; i.e. 3.5 mm or more)
• Monochorionic twins
• Crown-rump length discordancy >10% in dichorionic twin pregnancies

Where it is running

• University of Alabama — Birmingham, Alabama, United States
• University of California-Long Beach — Long Beach, California, United States
• University of California, Irvine Medical Center — Orange, California, United States
• Christiana Care Health Services — Newark, Delaware, United States
• Northwestern University — Chicago, Illinois, United States
• National Institute of Child Health and Human Development (NICHD), 9000 Rockville — Bethesda, Maryland, United States
• Columbia University — New York, New York, United States
• Women and Infants — Providence, Rhode Island, United States
• Medical University of S. Carolina — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.