Effect of Interleukin-1 Receptor Antagonist on Inhalation of 20,000 EU Clinical Ctr Reference Endotoxin in Normal Volunteers

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy Control Subjects

In brief

The investigators want to see if healthy people who are given 2 doses of a medication called anakinra, which is used to treat moderate to severe rheumatoid arthritis, (RA) and then exposed to a form of air pollution, called Endotoxin, have less inflammation with the medication. Endotoxin is believed to be one of the causes of asthma attacks.

Key facts

Study ID

NCT01369017

Run by

Michelle Hernandez, MD

People needed

17

Starts

2011-10-01

Expected to finish

2013-07-01

Last updated by the study team

2013-07-15

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy volunteers
• age 18-50 years

You may not qualify if…

• asthma
• pregnant women
• smokers

Where it is running

• UNC Center for Environmental Medicine, Asthma and Lung Biology — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.