Prevention of West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH)

Status unconfirmed · Not applicable

Conditions studied: West Syndrome

In brief

West syndrome (WS) is a specific type of epilepsy (or seizure disorder) that has three features: infantile spasms (type of seizure), loss of milestones, and a specific pattern on electroencephalogram (EEG or brain wave test) called hypsarhythmia. The purpose of this study is to detect pre-hypsarhythmia in infants at high-risk for WS and determine whether treatment with ACTH will prevent WS.

Key facts

Study ID

NCT01367964

Run by

Ann & Robert H Lurie Children's Hospital of Chicago

People needed

28

Starts

2011-07-01

Expected to finish

2018-12-01

Last updated by the study team

2018-11-16

Who can join

Age: 0 and older, up to 1. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Infants with pre-hypsarhythmia (Type 3 EEG) between 2 months to 12 months of age.

You may not qualify if…

• Infants with any of the following diagnoses:
• A previous history of infantile spasms;
• Known inborn error of metabolism;
• Other symptomatic epileptic encephalopathy (e.g. Ohtahara syndrome).

Where it is running

• Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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