Intravenous (IV) Methylnaltrexone (MNTX) in the Prevention of Post-Operative Ileus

Completed · Phase 2 · Has a placebo group

Conditions studied: Postoperative Ileus

In brief

A double-blind, randomized, parallel-group study designed to evaluate the safety and activity of IV MNTX in the treatment of Post-Operative Ileus (POI) in patients who underwent segmental colectomies via laparotomy.

Key facts

Study ID

NCT01367548

Run by

Bausch Health Americas, Inc.

People needed

65

Starts

2003-07-01

Expected to finish

2004-12-01

Last updated by the study team

2019-11-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females, 18 yrs or older
• Patients who have undergone a segmental colectomy
• Must be receiving opioids via IV.

You may not qualify if…

• Patients who received any experimental drug in the last 30 days
• Patients receiving spinal medication for post-operative pain relief
• Patients who have undergone operations for complications related to inflammatory bowel disease
• Patients with recent history of abdominal radiation therapy.

Where it is running

• Progenics Pharmaceuticals, Inc. — Tarrytown, New York, United States

Full record on ClinicalTrials.gov

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