Ketamine Anesthesia in Electroconvulsive Therapy

Completed · Not applicable

Conditions studied: Depression

In brief

Does the use of ketamine as the anesthetic medication in electroconvulsive therapy (ECT) accelerate the antidepressant effect of ECT? The study hypothesis was that depressed subjects receiving ECT with ketamine as the anesthetic agent would demonstrate a faster rate of improvement, defined as lower depression ratings after the second ECT than depressed patients receiving ECT with the usual anesthetic agent.

Key facts

Study ID

NCT01367119

Run by

Mayo Clinic

People needed

38

Starts

2011-05-01

Expected to finish

2012-03-01

Last updated by the study team

2013-08-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of depression, either unipolar or bipolar
• Subjects receiving ECT at the Mayo Clinic

You may not qualify if…

• Subjects not giving their own consent to ECT
• Subjects with schizophrenia, schizoaffective disorder, or dementia
• Subjects diagnosed with a major neurological disorder such as epilepsy, Parkinson disease, multiple sclerosis, or a neurodegenerative dementia.

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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