Natural History of HPV From Infection to Neoplasia in Adolescents and Young Women
Completed
Conditions studied: Human Papillomavirus, CIN 2, CIN 3
In brief
The natural history of human papillomavirus (HPV) is most likely influenced by both innate and adaptive mucosal immunity. More specifically, we hypothesize that Toll like receptors (TLR) play an important role in cervical innate immunity to HPV through secretions of proinflammatory, chemotactic and anti-viral cytokines. Up-regulated TLR expression will also result in activation of dendritic cells and T cells that in turn will promote a T helper (Th) l like response through secretion of several cytokines and consequently, the induction of a successful cell mediated immune (CMI) response.
Key facts
- Study ID
- NCT01366742
- Run by
- University of California, Los Angeles
- People needed
- 900
- Starts
- 1987-12-01
- Expected to finish
- 2016-05-01
- Last updated by the study team
- 2016-05-17
Who can join
Age: 13 and older, up to 22. Sex: female. Healthy volunteers: accepted.
Where it is running
- SFSU Student Health Center — San Francisco, California, United States
- HPV Study - San Leandro Office — San Leandro, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.