Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients
Status unconfirmed · Not applicable
Conditions studied: Muscle Weakness, Critical Illness, Respiratory Insufficiency
In brief
The investigators hypothesize that by applying a validated algorithm to accomplish early mobilization in surgical intensive care unit (ICU) patients, these patients will achieve a higher level of mobility which translates to shorter ICU length of stay and improved functional status at discharge. Additionally, the investigators hypothesize that genetic polymorphisms related to muscle strength and sleep will also explain some variance in these outcome variables.
Key facts
- Study ID
- NCT01363102
- Run by
- Massachusetts General Hospital
- People needed
- 200
- Starts
- 2011-06-01
- Expected to finish
- 2016-12-01
- Last updated by the study team
- 2016-03-17
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (18 years of age or greater)
- Who have been on mechanical ventilation for less than 48 hours and are expected to continue for at least 24 more hours
- Who meet criteria for baseline functional independence (Barthel Index greater than or equal to 70 obtained from a proxy describing patient function 2 weeks before admission
You may not qualify if…
- Irreversible disorders with 6-month mortality greater than 50%
- Rapidly developing neuromuscular disease
- Cardiopulmonary arrest
- Motor component of Glascow Coma Scale <5
- Elevated intracranial pressure
- Ruptured/leaking aortic aneurysm
- Acute MI before peak troponin has been reached
- Absent lower limbs
- Pregnancy
- Unstable fractures contributing to likely immobility
- Hospitalization prior to ICU admission >5 days
- Enrollment in another clinical trial
Where it is running
- The Massachusetts General Hospital — Boston, Massachusetts, United States
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
- University of Massachusetts — Worcester, Massachusetts, United States
- University of Salzburg — Salzburg, Austria
- Technische Universität München — München, Bavaria, Germany
Full record on ClinicalTrials.gov
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