Genotypic and Phenotypic Correlates of Resistance to Aspirin

Completed · Not applicable

Conditions studied: Platelet Dysfunction Due to Aspirin

In brief

The study seeks to identify genomic markers associated with aspirin resistance.

Key facts

Study ID

NCT01361620

Run by

George Washington University

People needed

190

Starts

2007-12-01

Expected to finish

2011-04-01

Last updated by the study team

2013-12-16

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Volunteers 40 to 80 years old willing to sign consent and take 81 mg of aspirin for 7 - 10 days and return for laboratory testing.

You may not qualify if…

• Patient requiring more than 81 mg aspirin daily
• Known GI bleeding attributed to ASA
• Active peptic ulcer disease or history within the last year
• Known aspirin allergy
• Current use of:
• warfarin,
• heparin,
• NSAIDs (except aspirin),
• clopidogrel,
• dipyridamole,
• fish-oil/omega 3 supplements,
• Women of childbearing potential who are pregnant, planning to become pregnant or nursing.

Where it is running

• GWU Medical Faculty Associates — Washington D.C., District of Columbia, United States

Full record on ClinicalTrials.gov

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