Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates

Withdrawn before enrolling · Phase 3 · Has a placebo group

Conditions studied: Tube Feeding

In brief

It is hypothesized that using methylnaltrexone in addition to pain killer narcotics (opiates) in patients will result in increased tube feeding rates with more frequent nutrition at goal calorie rate.

Key facts

Study ID

NCT01360372

Run by

Drexel University

People needed

0

Starts

2010-10-01

Expected to finish

2012-05-01

Last updated by the study team

2015-03-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Inadequate tube feeding rate of greater than equal to 40% below goal rate.
• Prescribed opiate therapy for pain or sedation, stable dose for minimum 48 hours
• Stable dose or no dose laxative for minimum 72 hours

You may not qualify if…

• Unstable Hemodynamics (eg. vasopressor medication)
• Pregnancy
• End stage Renal Disease on Dialysis
• Plan to wean opiates in next 48 hours
• Known or suspected mechanical gastrointestinal obstruction
• Initial expired hydrogen breath level greater than 20

Where it is running

• Hahnemann University Hospital — Philadelphia, Pennsylvania, United States
• Cancer Treatment Center of America — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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