Genes and Environment in Multiple Sclerosis
Recruiting now
Conditions studied: Multiple Sclerosis
In brief
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS will be beneficial in the future if the investigators can identify effective ways to prevent or slow down the progression of this disease.
Key facts
- Study ID
- NCT01353547
- Run by
- Columbia University
- People needed
- 5000
- Starts
- 2017-10-01
- Expected to finish
- 2040-10-01
- Last updated by the study team
- 2026-05-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- First Degree Relatives of Patients with MS, or
- Patients who have received anti-TNFa therapy as treatment for inflammatory diseases other than MS such as Crohn's disease, psoriasis and rheumatoid arthritis, or
- Patients that have been referred for an evaluation of first presentation of neurologic symptoms but do not have a diagnosis of MS
- Live in the United States
You may not qualify if…
- Does not match any of the inclusion criteria
Where it is running
- National Institute of Neurological Disorders and Stroke — Bethesda, Maryland, United States (enrolling)
- Columbia University Irving Center — New York, New York, United States (enrolling)
- University of Pittsburgh — Pittsburgh, Pennsylvania, United States (enrolling)
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Brigham and Women's Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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