Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Completed · Phase 1

Conditions studied: Drug Drug Interaction

In brief

Study evaluates the drug-drug interaction between Ticagrelor and Venlafaxine when taken together in healthy volunteers

Key facts

Study ID

NCT01350921

Run by

AstraZeneca

People needed

22

Starts

2011-05-01

Expected to finish

2012-03-01

Last updated by the study team

2012-03-30

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• a weight of at least 50 kg and a body mass index between 18 to 30 kg/m2

You may not qualify if…

• History of clinically significant disease or disorder as judged by the investigator
• Any clinically significant illness, medical/surgical procedure or trauma within 4 weeks of the first administration of drug.
• History of haemophilia, von Willebrand´s disease, lupus anticoagulant or other diseases/syndromes that may alter or increase bleeding.
• History of previous or ongoing psychiatric disease

Where it is running

• Research Site — Overland Park, Kansas, United States
• Research Site — Uppsala, Sweden

Full record on ClinicalTrials.gov

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