Effect of the Direct Renin Inhibitor Aliskiren on Endothelial Function and Arterial Stiffness in Diabetic Subjects

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Diabetes, Pre-hypertension, Hypertension

In brief

The study will evaluate the effects of the direct renin inhibitor, aliskiren, on flow-mediated dilation of the brachial artery and on central aortic pressure in diabetic patients with pre-hypertension or Stage 1 hypertension.

Key facts

Study ID

NCT01349114

Run by

University of Alabama at Birmingham

People needed

21

Starts

2011-06-01

Expected to finish

2012-01-01

Last updated by the study team

2017-05-11

Who can join

Age: 19 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Type 2 diabetes
• prehypertension or Stage 1 hypertension

You may not qualify if…

• Type 1 diabetes
• Stage 2 hypertension
• CKD
• recent MI, revascularization, CVA or TIA

Where it is running

• UAB — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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