The Impact of Fitness on Vascular Dysfunction in Adolescents With Type 1 Diabetes

Completed

Conditions studied: Type 1 Diabetes

In brief

The principal hypothesis of this study is that the micro and macro vasculature of young diabetes mellitus type 1 (DM1) patients is particularly susceptible to atherogenic factors which cause vascular dysfunction at multiple levels of the arterial vasculature and that this dysfunction is demonstrable using state-of-the-art ultrasound methods. The investigators further hypothesize that interventions, such as exercise, that are readily integrated into the daily life of individuals with DM1 can mitigate or reverse these early vascular changes and thereby diminish the otherwise predictable longer-term development of cardiovascular disease (CVD) in type 1 DM

Key facts

Study ID

NCT01337947

Run by

University of Virginia

People needed

32

Starts

2011-04-01

Expected to finish

2013-11-01

Last updated by the study team

2014-09-29

Who can join

Age: 12 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• under 12 or over 18 years of age
• medication that could affect the blood vessels
• smoker
• above average BMI
• chronic illness other than DM1

Where it is running

• University of Virginia — Charlottesville, Virginia, United States

Full record on ClinicalTrials.gov

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