Human Circadian Sensitivity to Very Short Light Pulses

Completed · Not applicable

Conditions studied: Circadian Rhythm Disorders

In brief

The mammalian eye serves both visual and non-image-forming functions. New information about the non-image-forming anatomy and physiology of the eye has revealed effects of ocular light stimuli on human circadian rhythms, melatonin suppression, heart rate, pupillary reflexes, cognitive performance, alertness and sleep. The results of the proposed work can be used to make predictions about the effects of light, to make recommendations involving exposure to or avoidance of light, and to design environmental lighting, resulting in improved health and alertness and decreased errors and accidents.

Key facts

Study ID

NCT01330992

Run by

Brigham and Women's Hospital

People needed

400

Starts

2009-12-01

Expected to finish

2011-08-01

Last updated by the study team

2011-08-23

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy volunteers

You may not qualify if…

• No medications
• No eye disease
• No sleep disorders
• No psychiatric disorders

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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