Effect of Diet Orange Soda on Urinary Lithogenicity

Completed · Not applicable

Conditions studied: Kidney Stones, Nephrolithiasis, Urolithiasis

In brief

Beverages containing citrate may be useful in increasing urine citrate content and urine pH. Such changes in urine chemistry could help prevent kidney stones. Diet orange soda has more citrate than other similar beverages. The investigators are interested in whether diet soda will improve urine chemistry in the appropriate manner.

Key facts

Study ID

NCT01330940

Run by

VA New York Harbor Healthcare System

People needed

12

Starts

2009-11-01

Expected to finish

2010-07-01

Last updated by the study team

2012-09-10

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-65 years old
• able to sign consent
• ability to reliably urinate into a vessel and measure urine volume

You may not qualify if…

• prior history of nephrolithiasis
• a known history of metabolic bone disease
• hyperthyroidism
• hyperparathyroidism or chronic kidney disease
• current use of diuretics
• current use of potassium citrate or other oral alkali supplementation and
• use of calcium supplementation that could not be stopped

Where it is running

• New York Harbor VA Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

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