Light Sensitization Study

Completed · Not applicable

Conditions studied: Chronobiology Disorders, Circadian Rhythm Disorders, Sleep Disorders, Circadian Rhythm

In brief

Circadian rhythm disorders are a class of sleep disorders characterized by misalignment between the timing of sleep and the timing of rhythms driven by the biological clock. Light therapy can effectively treat these disorders, but the intensity and duration of light exposure required to do so has limited its practical use. In this study the investigators will test whether pre-exposure to dim light may enhance the response of the circadian system to light therapy. If so, this could result in shorter treatments that would have greater practical applications.

Key facts

Study ID

NCT01327040

Run by

Brigham and Women's Hospital

People needed

32

Starts

2010-10-01

Expected to finish

2020-12-01

Last updated by the study team

2021-07-01

Who can join

Age: 21 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy adults with conventional and regular sleep-wake timing
• non-smokers
• completion of medical, psychological, ophthalmological, and sleep screening tests
• able to spend 13 consecutive days/nights in the laboratory

You may not qualify if…

• history of neurological or psychiatric disorder
• history of eye injury, eye surgery, or visual disorder (corrective lenses are acceptable)
• history of sleep disorder or regular use of sleep-promoting medication
• current prescription, herbal, or over-the-counter medication use (oral contraceptives are acceptable)

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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