Task-oriented Training for Stroke: Impact on Function Mobility

Completed · Not applicable

Conditions studied: Cerebrovascular Accident, Stroke

In brief

Residual neurological deficits from stroke lead to gait inefficiencies, resulting in an extremely high energy cost of movement and contributing to overall disability and lower quality of life. Therefore, interventions targeting movement economy should be developed for those in the chronic phase of stroke recovery. This study is designed to compare the effect of two distinctly different exercise paradigms (a higher-intensity treadmill training program and a lower-intensity group exercise program) on economy of movement during over-ground walking and activities of daily living, as well as the extent to which gains in muscular strength, muscular endurance, and balance predict changes in movement economy.

Key facts

Study ID

NCT01322607

Run by

VA Office of Research and Development

People needed

20

Starts

2011-07-01

Expected to finish

2015-01-01

Last updated by the study team

2016-04-06

Who can join

Age: 40 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Stroke > 6 months prior with residual hemiparetic gait in women or men aged 40-85 years.
• Completion of all regular post-stroke physical therapy
• Adequate language and neurocognitive function to participate in testing and training and to give adequate informed consent.
• Able to rise from a chair unaided.
• Able to walk 10 meters without human assistance.

You may not qualify if…

• Regular structured aerobic exercise (> 2x week).
• Alcohol consumption > 3 oz. liquor, or 3 x 4 oz glasses of wine, or 3 x 12 oz. beers per day, by self-report.
• Clinical history of
• unstable angina,
• recent (< 3 months) myocardial infarction or congestive heart failure (NYHA category II),
• hemodynamically significant valvular dysfunction,
• Peripheral Arterial Obstructive Disease with claudication,
• major orthopedic, chronic pain, or non-stroke neuromuscular disorders restricting exercise,
• pulmonary or renal failure,
• poorly controlled hypertension (>190/110), measured on at least two separate occasions
• recent hospitalization for severe disease or surgery
• severe or global receptive aphasia which confounds reliable testing and training.
• Untreated major depression as documented by a Center for Epidemiological Studies-Depression score of >16 and confirmed by clinical interview.
• Pregnancy.

Where it is running

• Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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