A Study of Chewing Gum, Snacking and Appetite
Completed · Not applicable
Conditions studied: Hunger
In brief
Investigators are interested in learning how appetite responds after chewing gum. In this research study subjects will be asked to eat a lunch meal provided at our Center. After eating the lunch meal, subjects will answer questions describing their feelings of hunger, thirst and desire to eat every 30 minutes for 3 hours. Blood will be drawn throughout the study period to determine how chewing gum impacts certain hormones released from your intestine after eating and therefore how they influence your appetite. Blood draws will be done every 30 minutes for 3 hours. At only one of the two study visits, subjects will chew gum during specific times. One study visit will not include chewing gum. After three hours, there will be a snack to eat as much as desired followed by one more set of questions and blood draw. All study visits will take approximately 4 ½ hours.
Key facts
- Study ID
- NCT01316991
- Run by
- Clinical Nutrition Research Center, Illinois Institute of Technology
- People needed
- 57
- Starts
- 2010-12-01
- Expected to finish
- 2015-09-01
- Last updated by the study team
- 2021-08-06
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Females
- 18 years of age and older
- Healthy weight: BMI between 18.5 and 24.9 kg/m2, inclusive
- Obese: BMI between 30 - 38 kg/m2, inclusive
- No clinical evidence of cardiovascular, metabolic, respiratory, renal, gastrointestinal or hepatic disease
- Unrestrained eater (score < 10 on the Three Factor Eating Questionnaire)
You may not qualify if…
- Pregnant and/or lactating or planning for pregnancy
- Allergies or intolerances to foods consumed in the study
- Fasting blood glucose > 110 mg/dL. Subjects identified with elevated fasting blood glucose levels will be will be advised to contact their primary care physician for appropriate follow-up care.
- Taking over the counter supplements that may interfere with the study procedures or endpoints
- Taking prescription medications that may interfere with study procedures or endpoints (medications that affect appetite, unstable dose of hormones <6 months)
- Subjects with unusual dietary habits (e.g. pica)
- Actively losing weight or trying to lose weight (unstable body weight fluctuations of > 5 kg in a 60 day period)
- Excessive exercisers or trained athletes
- Addicted to drugs and/or alcohol
- Medically documented psychiatric or neurological disturbances
- Smoker (past smoker may be allowed if cessation is > 2 years)
Where it is running
- Clinical Nutrition Research Center — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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