Effects of Intensive Behavioral Training Program on Impulsivity and Inhibitory Control in Smokers
Status unconfirmed · Not applicable
Conditions studied: Tobacco Smoking, Nicotine Dependence, Impulsivity, Addiction, Substance Dependence
In brief
Dependence on tobacco derived nicotine is a major public health problem. Substance users who complete training in mindfulness subjectively report increased patience and improved motor control over their impulses. Yet, no studies have tested this perceived benefit with behavioral measures of impulse control. The investigators are conducting a randomized controlled clinical trial, which compares Cognitive-Behavioral Therapy and Mindfulness Training for tobacco smokers, using behavioral measures to investigate the effects of mindfulness training on impulsivity and inhibitory control.
Key facts
- Study ID
- NCT01314378
- Run by
- Massachusetts General Hospital
- People needed
- 72
- Starts
- 2011-01-01
- Expected to finish
- 2012-10-01
- Last updated by the study team
- 2012-05-02
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Women and men aged 18-65, inclusive, who are competent, wish to participate and willing to provide informed consent.
- Self report smoking >=15 cigarettes/day.
- Expired air CO > 9ppm at the time of enrollment.
You may not qualify if…
- DSM-IV diagnosis of dementia, neurodegenerative disease, or other organic mental disorder, lifetime history of psychotic disorder, bipolar disorder, severe PTSD, Dissociative Identity Disorder, OCD, anorexia nervosa, mental retardation, or autism. History of moderate or severe major depressive episode or generalized anxiety disorder within the last 6 months. Currently symptomatic ADHD with either current stimulant treatment or a history of stimulant treatment for greater than 1 year.
- Use of prescribed psychotropic medication other than SSRI/NDRI/SNRI/buprenorphine in past 6mo, or change in such psychiatric medication dose in past six months.
- Reported history of active substance use disorder other than nicotine or caffeine in the last six months.
- Positive urine toxicology for illicit drugs, alcohol, opiates or benzodiazepines. (This does not include buprenorphine if participant can demonstrate 6 months of addiction treatment with negative urine screens. With the consent of the participant, participation will be discussed with the potential subject's addiction treatment provider prior to initiation of interventions.)
- Serious unstable medical illness including, cardiovascular, hepatic, renal, respiratory, endocrine, neurological, or hematological disease such that hospitalization for treatment of that illness is likely within the next 4 months. History of life-threatening arrhythmia, CHF, syncope, or myocardial infarction within the last year. Abnormal cardiovascular event, or uncontrolled hypertension within last 2 months.
- History of either cerebrovascular events (i.e., stroke, TIA) or head injuries with lasting neurological sequelae; history of seizure disorder or current CNS tumor.
- Use of investigational medication in the past 30 days.
- Third trimester pregnancy.
- Inability to speak, read, or understand English.
Where it is running
- MGH Center for Addiction Medicine — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.