Genetics Study of Wet Age-Related Macular Degeneration (AMD) Non-Responders to Vascular Endothelial Growth Factor (VEGF) Therapy

Status unconfirmed

Conditions studied: Wet AMD

In brief

To obtain a genotypic analysis of patients with chronic exudative age-related macular degeneration noted to have subretinal or intraretinal edema despite continuous monthly Anti-VEGF therapy.

Key facts

Study ID

NCT01310686

Run by

West Coast Retina Medical Group, Inc.

People needed

40

Starts

2011-04-01

Expected to finish

2019-06-01

Last updated by the study team

2018-10-12

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Ability to provide written informed consent for participation in this study
• Subjects diagnoses of neovascular AMD who are on a monthly anti-VEGF regimen (have had >10 or more ranibizumab and/or bevacizumab injections within the last year) and who still have intra-retinal or subretinal fluid as confirmed by the Investigator

You may not qualify if…

• Subjects with a Pigment Epithelial Detachment Exclusively
• Subjects with Serous Pigment Epithelial Detachments
• Subjects with history of the following:
• idiopathic polypoidal choroidal vasculopathy
• pathologic degenerative myopia
• central serous chorioretinopathy
• familial drusen
• adult onset foveal pattern dystrophy

Where it is running

• West Coast Retina Medical Group, Inc. — San Francisco, California, United States

Full record on ClinicalTrials.gov

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