Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit

Completed · Not applicable · Has a placebo group

Conditions studied: Tobacco Use Disorder

In brief

The investigators will randomize smokers to receive 1) Varenicline + smoking cessation/reduction counseling or 2) Placebo pill + smoking cessation/reduction counseling. Neither the participants nor the research therapists/evaluators will know to which condition (active or placebo pill) the participants have been assigned i.e., a double-blind study). The medication and weekly counseling will occur for 28 days. Participants will complete assessment measures just before the start of treatment (baseline), at the end-of-treatment, at 1-month, 3-month, and at 6-months to determine if there are differences in tobacco use between treatment groups.

Key facts

Study ID

NCT01308736

Run by

Rutgers, The State University of New Jersey

People needed

73

Starts

2011-01-01

Expected to finish

2014-02-01

Last updated by the study team

2017-07-17

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must smoke at least 10 cigarettes per day for past 6-months
• Must have a working cellular or land-line phone

You may not qualify if…

• Must not be thinking of quitting in the next 30 days, but be interested in cutting down- Must not regularly (more than 1x/month) use tobacco products other than cigarettes
• Must not be currently receiving tobacco dependence treatment counseling
• Must not currently be taking varenicline, bupropion, nortriptyline, or any nicotine preparations (gum, lozenge, patch, spray, inhaler)
• Must not have positive screen on SCID-I/NP Psychotic Screen
• Must have no contraindications to using varenicline, including pregnancy, as measured by Medical History Form

Where it is running

• Division of Addiction Psychiatry — New Brunswick, New Jersey, United States

Full record on ClinicalTrials.gov

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