Effect of Supplemental Oxygen on Maximal Oxygen Consumption in Patients With Chronic Obstructive Pulmonary Disease

Completed · Not applicable

Conditions studied: Chronic Obstructive Pulmonary Disease

In brief

Maximal consumption of oxygen (VO2max) during exercise is used in patients with chronic obstructive pulmonary disease (COPD) to stratify perioperative risk. However, the impact of supplemental oxygen to prevent hypoxemia during exercise on maximal oxygen consumption and other ventilatory parameters during maximal exercise in the resting normoxic Chronic Obstructive Pulmonary Disease population is poorly defined. The investigators performed a randomized controlled trial in patients with COPD who underwent cardiopulmonary exercise tests on room air and supplemental oxygen. The investigators compared maximal oxygen consumption and other ventilatory parameters in each individual subject under the two conditions.

Key facts

Study ID

NCT01294033

Run by

Beth Israel Deaconess Medical Center

People needed

20

Starts

2009-08-01

Expected to finish

2010-07-01

Last updated by the study team

2017-03-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of Chronic Obstructive Pulmonary Disease (COPD).
• Pulmonary function characterized by forced expiratory volume in 1 second/forced vital capacity ratio<0.7, and forced expiratory volume in one second <80% predicted.

You may not qualify if…

• Subjects with a recent COPD exacerbation requiring emergency department visit or hospitalization within the last month.
• Subjects scheduled for a major pulmonary intervention in the next 3 months
• Subjects with severe peripheral vascular disease or other physical conditions that would preclude exercise testing

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.