Evaluation of Phenotypic and Genetic Properties in Male Subjects Affected by Hypohidrotic Ectodermal Dysplasia - A

Completed

Conditions studied: Hypohidrotic Ectodermal Dysplasia

In brief

The overall purpose of this study is to learn more about Hypohidrotic Ectodermal Dysplasia (HED) and to help in identifying treatment opportunities. Several evaluations will be conducted in this study: 1) the number of skin sweat glands you have and their ability to produce sweat; 2) your ability to grow hair; 3) the structure of your face compared to faces of people affected by HED; 4) molds of your teeth to see if and how they are different than people affected by HED.

Key facts

Study ID

NCT01293565

Run by

Edimer Pharmaceuticals

People needed

27

Starts

2011-02-01

Expected to finish

2011-07-01

Last updated by the study team

2012-06-28

Who can join

Age: 14 and older, up to 29. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Males age 14-29 years with clinical diagnosis of HED
• No scalp shaving in the 6 months prior to enrollment
• No current medical therapy for hair loss
• Written informed consent for study and genotyping (or signed medical release of previous genetic test results)

You may not qualify if…

• Medically significant condition as determined by the PI
• Known hypersensitivity to pilocarpine or pilocarpine-like muscarinic agonists (e.g. Urecholine, Salagen, Pilocar, Provocholine)
• Presence of cardiac pacemaker

Where it is running

• University of California — San Francisco, California, United States

Full record on ClinicalTrials.gov

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